This work analyses the prominent characteristics of extreme storms and flash-flood regimes in two main areas of the Mediterranean region: the North-Western (comprising Spain, France and Italy) and South-Eastern region (Israel). The two areas are chosen to represent the two end members of variation in flash-flood regimes in the Mediterranean basin. Data from 99 events collected in the two areas (69 from the North-Western region and 30 from the South-Eastern region), for which occurrence date, catchment area and flood peak are available, were used to provide a detailed description the flash-flood seasonality patterns, the synoptic and mesoscale atmospheric controls, and flood envelope relationship. Results show that the flood envelope curve for the South-Eastern region exhibits a more pronounced decreasing with catchment size with respect to the curve of the North-Western region. The differences between the two relationships reflect variations in the fractional storm coverage of the basin and hydrological characteristics between the two regions. Seasonality analysis shows that the events in the North-Western region tend to occur between August and November, whereas those in the South-Eastern area tend to occur in the period between October and May, reflecting the relevant patterns in the synoptic conditions controlling the generation of intense precipitation events.